WE STRIVE TO PREVENT AND CURE DEMENTIA

For decades, Eisai has led the way in dementia research and development. Now we’re broadening our scope, taking a multi-dimensional, targeted path to our ultimate goal: prevention and a cure. Here’s a quick look at what we’re working on right now.



Blood Test for Alzheimer

A BLOOD TEST FOR ALZHEIMER’S?

We’re collaborating with Sysmex on a potential blood-based test for predicting amyloid pathology. This automated immune-assay system under investigation could also be utilized as a simpler and more cost-effective method to identify participants for clinical trials exploring a variety of AD therapies now in development.




Critical insights from leading experts about the science behind the Aβ pathway in Alzheimer’s disease

Reflecting over three decades of progress in molecular medicine, amyloid-β (Aβ) remains the hallmark of Alzheimer’s disease (AD) pathology and is the leading target for developing potential disease-modifying therapies. Presented at the 15th International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PDTM 2021), the presentations summarize the latest updates and supporting evidence of the role of Aβ in AD by synthesizing the existing and new translational & cross-disciplinary data-driven studies.

“Extensive evidence indicates that Aβ accumulation in the brain is one of the earliest pathophysiological changes in the Alzheimer’s disease continuum, and that early targeting of the pathway may provide a promising therapeutic approach to prevent or slow down the clinical biological progression of the disease.”

Dr. Harald Hampel
Chief Medical Officer
Neurology Business Group







Alzheimer’s disease: global impact, pathophysiology, and the evolving clinical care

Alzheimer’s disease is a growing global health challenge and has an enormous impact on patients and family members, healthcare systems and society at large. In the three videos below, Dr. Harald Hampel, Vice President and Chief Medical Officer of the Neurology Business Group, and a global expert in Alzheimer’s Disease discusses the global impact of dementia due to Alzheimer’s and other neurodegenerative diseases. In addition, he presents existing multi-disciplinary evidence that supports the role of the amyloid-β pathway in Alzheimer’s disease pathophysiology and therapy development. Finally, he provides future perspectives on Alzheimer’s disease research and clinical care.






Learn from leading AD experts about the AT(N) system and how it may shape clinical practice and therapy development

Discover the AT(N) system – a biomarker-based classification system that classifies individuals using core AD pathophysiological features: amyloid-β(A), tau (T) and neurodegeneration (N). Presented at the 2020 Alzheimer’s Association International Conference (AAIC), the three presentations provide a state-of-the-art overview on the validation and qualification of the AT(N) system and its evolution to ATX(N) for AD clinical practice and therapy development.

“The AT(N) system offers a framework to define Alzheimer’s disease in a continuum using biologically rooted measurements. It circumvents the limitations of the traditional, clinical phenotype-based approach, and has the potential to facilitate therapeutic interventions at the early stages of the disease.”

Harald Hampel
Chief Medical Officer
Neurology Business Group